Amit Tirosh

Prof. Amit Tirosh is a endocrinologist and Head of the Neuroendocrine Tumors Service at Sheba Medical Center. He is an authority on von Hippel–Lindau (VHL) disease and hereditary endocrine syndromes. Prof. Tirosh contributed to the global clinical guidelines for managing VHL patients.

Specialization and Oncology Services

Prof. Tirosh treats neuroendocrine tumors (NETs). He specializes in hereditary syndromes, including MEN1 and VHL disease. He serves as the primary contact for the multidisciplinary VHL clinic at Sheba. The specialist offers treatments such as Peptide Receptor Radionuclide Therapy (PRRT).

PRRT is a molecular therapy that delivers radiation directly to cancer cells. The doctor treats a range of conditions, including:

• Pancreatic neuroendocrine tumors
• Adrenal adenomas
• Pancreatic, stomach, and colon cancers
• Kidney and testicular cancers
• Small intestine cancer

He uses diagnostic tools such as PET-CT with Gallium 68 and whole-body MRI. His therapeutic approach includes Lutetium-177 therapy and targeted biological treatments.

Academic and Research Leadership

The specialist leads the Endocrine Oncology Bioinformatics Lab. He investigates new data-driven methods to treat endocrine cancers. Dr. Tirosh collaborates with the Weizmann Institute of Science and teams in Italy and Germany. Additionally, he lectures at Tel Aviv University’s Faculty of Medicine.

Professional History

• Head of Neuroendocrine Tumors Service – Sheba Medical Center
• Affiliated Researcher – National Institutes of Health (NIH), USA
• Faculty Member – Tel Aviv University
• Endocrinology Fellow – Rabin Medical Center
• Internal Medicine Resident – Assaf HaRofeh Medical Center

Education and Training

• Doctor of Medicine – Hadassah Medical School, Hebrew University of Jerusalem
• Specialty Training – Internal Medicine, Assaf HaRofeh Medical Center
• Fellowship – Endocrinology, Rabin Medical Center
• Advanced Training – Neuroendocrine Tumors and Genetics, National Institutes of Health (USA)
• Board Certification – Endocrinology

Publications and Memberships

Prof. Tirosh has authored over 40 peer-reviewed papers. His research appears in journals such as JAMA, Gastroenterology, Radiology, and Oncology. Notable works include studies on VHL-associated tumors and radioguided surgery for NETs.

He is a member of several professional organizations:

• European Neuroendocrine Tumor Society
• American Endocrine Society
• Israeli Society of Endocrinology