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Westpfalz-Klinikum GmbH is a multi-specialty hospital group in Kaiserslautern, Germany. It treats adults and children across four locations. The hospital specializes in oncology, cardiology, and orthopedics. It is an academic teaching hospital for Johannes Gutenberg-Universität Mainz. The facility opened in 1893. Its central emergency department treats about 60,000 patients each year.

The group runs 1,391 inpatient beds. Surgeons perform over 19,000 anesthesia services each year at the main center. The hospital holds a certified endoprosthetics center of maximal care. Specialists use Da Vinci robotic systems for urology and gynecology. The oncology unit offers radiosurgery with CyberKnife technology. Diagnostics include PET-CT with Gallium 68 for precise tumor imaging.