Sheba Pediatric CAR-T Program for Multiple Myeloma

• العلاج بالخلايا التائية ذات مستقبل المستضد الخيمري
• فحص الأجسام المضادة لفيروس نقص المناعة البشرية
• فحص الأجسام المضادة لفيروس التهاب الكبد B
• فحص الأجسام المضادة لفيروس التهاب الكبد C
• فحص دم
• فحص كيمياء الدم
• خزعة
• تصوير الصدر بالأشعة السينية
• فحص تعداد الدم الكامل
• استشارة طبيب أورام
• استشارة طبيب أمراض دم
• طبيب حساسية ومناعة
• استشارة طبيب قلب
• استشارة طبيب أمراض دم أطفال
• استشارة طبيب أطفال
• تعداد الدم الكامل مع كشف أوسام الأورام السرطانية بالإضافة إلى تحليل البروتينات
• تخطيط كهربية القلب
• تخطيط كهربية القلب
• تصوير بالرنين المغناطيسي للرأس
• استشارة طبيب سرطان الدم
• تصوير مقطعي بالإصدار البوزيتروني

• 21 ايام في المستشفى

• نقل المطار والعيادة والمطار

Sheba Pediatric CAR-T Program for Multiple Myeloma

At Sheba Medical Center, children and young patients with multiple myeloma have access to one of the most advanced and trusted CAR-T therapy programs in the world. While multiple myeloma is more common in adults, Sheba provides highly specialized care for young and complex cases, including relapsed or treatment-resistant disease.

A Personalized Treatment Designed for Each Patient

CAR-T therapy uses the patient’s own immune system to recognize and destroy cancer cells. For patients with multiple myeloma, this innovative approach offers a highly targeted option when standard treatments are no longer effective.

At Sheba, the entire CAR-T process is performed on-site, ensuring speed, precision, and optimal cell quality:

Apheresis – collection of the patient’s T-cells
Cell Engineering – genetic modification at Sheba’s Advanced Biotherapy Center
Infusion – reintroduction of modified cells to target myeloma cells

Because no steps are outsourced, treatment can begin quickly and is typically completed within ~10 days. CAR-T functions as a “living therapy,” continuing to work in the body and offering the potential for long-term disease control and remission.

Expert Pediatric Leadership and Care

The program is led by Prof. Amos Toren, a globally recognized expert in pediatric hemato-oncology and cellular therapies, with decades of experience and over 1,500 bone marrow transplants performed.

Patients are treated within a highly specialized environment that includes:

Dedicated pediatric and young adult CAR-T units with 24/7 monitoring
A multidisciplinary team of hemato-oncologists, immunologists, and supportive care specialists
A patient- and family-centered approach, ensuring comfort and continuous support
Full international patient services, including travel and care coordination
Advanced Expertise in Complex Cases

Sheba is a global leader in CAR-T therapy, with strong clinical outcomes across hematologic cancers:

~90% remission in pediatric patients
~80% in young adults (up to 23 years)
~70% in adults

The program is experienced in managing rare, complex, and high-risk myeloma cases, offering advanced treatment options when other therapies have been exhausted.

Comprehensive Evaluation and Ongoing Support

Each patient undergoes a detailed diagnostic evaluation, including:
advanced imaging, bone marrow testing, genetic and molecular profiling, and full cardiac and pulmonary assessment.

Care is provided in English, Russian, and Arabic, ensuring clear communication and a supportive experience for international families.

A Trusted Place for Advanced Care

By combining cutting-edge science, rapid access to therapy, and compassionate care, Sheba offers one of the most advanced CAR-T programs for multiple myeloma focused on improving outcomes and helping patients return to a better quality of life.

• منسق طبي خاص
• ترتيبات السفر الطبي - حجز تذاكر السفر الجوي وغرف الفنادق بأسعار خاصة للشركاء
• دعوة المريض أثناء السفر الطبي