أفضل التصوير الشعاعي للثدي التشخيص - توب -189 أطباء

الدكتورة مانويلا سيفرت هي أخصائية ألمانية رائدة في مجال الثدي.

تخصص

الدكتورة مانويلا سيفرت متخصصة في التشخيص والعلاج والرعاية اللاحقة لأمراض الثدي والتصوير بالموجات فوق الصوتية.

يطبق الدكتور سيفر عمليات الحفاظ على الثدي كطريقة علاج رئيسية.

خبرة في العمل

• منذ عام 2016 - رئيس عيادة الثدي في المركز الطبي في زولينجن
• 2012-2016 - أخصائي أمراض الثدي والشيخوخة في مستشفى جامعة هيليوس فوبرتال
• 2001-2012 - كبير أطباء أمراض النساء والتوليد في قسم أمراض النساء والتوليد في Klinikverbund St. Antonius und St. Josef GmbH.

تعليم

• كلية الطب بجامعة هاينريش هاينه - إجازة في الطب العام
• Klinikverbund St. Antonius und St. Josef GmbH - تخصص في أمراض النساء والتوليد.

Experience 

• 2016 - 2017

İSTİNYE UNIVERSITY FACULTY OF MEDICINE

• 2016 - 2017

Liv Hospital

• 2016 - 2017

Liv Hospital Ulus

• 2015 - 2016

Acıbadem Bodrum Hospital

• 2014 - 2015

Tatvan State Hospital

• 2013 - 2015

Tatvan State Hospital

• 2012 - 2013

CLEVELAND CLINIC

• 2007 - 2014

Dokuz Eylul University Faculty of Medicine

Education 

• 2013

DOKUZ EYLÜL UNIVERSITY FACULTY OF MEDICINE, FACULTY OF MEDICINE/DEPARTMENT OF SURGICAL MEDICAL SCIENCES/DEPARTMENT OF GENERAL SURGERY

• 2013

Dokuz Eylül University, General Surgery

• 2007

AKDENİZ UNIVERSITY, FACULTY OF MEDICINE

• 2007

International Peer-Reviewed Journal Articles:

Title: The impact of sarcopenia on morbidity and long-term survival among patients with peritoneal metastases of colorectal origin treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a 10-year longitudinal analysis of a single-center experience.

• Authors: AĞALAR CİHAN, SÖKMEN SELMAN, ARSLAN ÖZŞAHİN NACİYE ÇİĞDEM, ALTAY CANAN, BAŞARA AKIN IŞIL, CANDA ARAS EMRE, OBUZ FUNDA
• Journal: Techniques in Coloproctology
• Year: 2020
• Volume: 24(4)
• Pages: 301-308
• DOI: 10.1007/s10151-020-02159-z
• Publication Number: 6776368

Title: Randomized controlled trial of 8 weeks’ vs 12 weeks’ interval between neoadjuvant chemoradiotherapy and surgery for locally advanced rectal cancer.

• Authors: Terzi Cem, Bingül Mustafa, ARSLAN NACİYE ÇİĞDEM, ÖZTÜRK ERSİN, CANDA ARAS EMRE, IŞIK ÖZGEN, YILMAZLAR AHMET TUNCAY, OBUZ FUNDA, Görken Birkay, KURT MERAL, ÜNLÜ ŞADİYE MEHTAT, UĞRAŞ NESRİN, Kanat Özkan, ÖZTOP İLHAN
• Journal: Colorectal Disease
• Year: 2020
• Volume: 22(3)
• Pages: 279-288
• DOI: 10.1111/codi.14867
• Publication Number: 6012919

Title: The effect of fibrin glue in preventing staple-line leak after sleeve gastrectomy: an experimental study in rats.

• Authors: ÖZDENKAYA YAŞAR, OLMUŞÇELİK OKTAY, BASIM PELİN, SAKA BURCU, ARSLAN NACİYE ÇİĞDEM
• Journal: Acta Cirurgica Brasileira
• Year: 2019
• Volume: 34(8)
• Publication Number: 5242669

Title: Treatment of intraoperatively detected peritoneal carcinomatosis of colorectal origin with cytoreductive surgery and intraperitoneal chemotherapy.

• Authors: CANDA ARAS EMRE, ARSLAN NACİYE ÇİĞDEM, Terzi Cem, Sokmen Selman, YAVUZŞEN TUĞBA, Ozkardesler Sevda, Unlu Mehtat, OBUZ FUNDA, FÜZÜN MEHMET
• Journal: World Journal of Surgical Oncology
• Year: 2018
• Volume: 16(1)
• Pages: 70-74
• DOI: 10.1186/s12957-018-1369-7
• Publication Number: 4863133

Title: Magnetic resonance-based pelvimetry and tumor volumetry can predict surgical difficulty and oncologic outcome in locally advanced mid–low rectal cancer.

• Authors: Atasoy Gulsen, ARSLAN NACİYE ÇİĞDEM, Elibol Funda, SAĞOL ÖZGÜL, OBUZ FUNDA, SÖKMEN SELMAN
• Journal: Surgery Today
• Year: 2018
• Volume: 48(12)
• Pages: 1040-1051
• DOI: 10.1007/s00595-018-1690-3
• Publication Number: 4863005

Title: Is advanced age a hesitation for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in colorectal cancer?

• Authors: Terzi Cem, Sokmen Selman, ARSLAN NACİYE ÇİĞDEM, Ozkardesler Sevda, DURAL CEMIL, OBUZ FUNDA, CANDA ARAS EMRE, GÖKTÜRK ÜMIT KELEŞTEN
• Journal: International Journal of Surgery
• Year: 2018
• Volume: 51
• Pages: 156-160
• DOI: 10.1016/j.ijsu.2018.01.010
• Publication Number: 4855751

Contributions to Conferences:

Title: Outcome of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal cancer: A single-center experience.

• Authors: CANDA ARAS EMRE, Sokmen Selman, Terzi Cem, ARSLAN NACİYE ÇİĞDEM, OBUZ FUNDA
• Conference: European Society of Surgical Oncology (ESSO) Congress
• Year: 2018
• Location: Budapest, Hungary

Title: Predictive factors for conversion to open surgery in laparoscopic colorectal surgery.

• Authors: ARSLAN NACİYE ÇİĞDEM, Terzi Cem, Sokmen Selman, CANDA ARAS EMRE, OBUZ FUNDA
• Conference: European Association for Endoscopic Surgery (EAES) Congress
• Year: 2017
• Location: Frankfurt, Germany

PROFESSIONAL EXPERIENCE

2011-2012
Erzurum Koprukoyu State Hospital
Department: General Medicine

2012-2017
Istanbul University Cerrahpaşa Medical Faculty
Department: Internal Medicine

06/2017-10/2017
Istanbul Gaziosmanpasa Taksim Training and Research Hospital
Department: Internal Medicine

10/2017-11/2018
Istanbul University Istanbul Medical Faculty
Department: Allergy and Immunology Fellowship

2018/2022
Istanbul University Oncology Institute
Department: Medical Oncology Fellowship

2022-2023
Tekirdag City Hospital
Department: Medical Oncology Specialist

2023-present
Istanbul Medipol University Medipol Bahcelievler Private Hospital
Department: Medical Oncology Assoc. Prof.

EDUCATION

2005-2011
Medical Education
Sivas Cumhuriyet University Medical Faculty, Sivas, Turkey

2012-2017
Internal Medicine
Istanbul University Cerrahpaşa Medical Faculty, Department of Internal Medicine, Istanbul, Turkey

2017-2018
Allergy-Immunology Fellowship
Istanbul University Istanbul Medical Faculty
Department of Internal Medicine, Division of Allergy and Immunology, Istanbul, Turkey

2018-2022
Medical Oncology Fellowship
Istanbul University Oncology Institute, Department of Medical Oncology, Istanbul, Turkey

2022
ESMO Board Certification in Medical Oncology
10th September 2022 in Paris, France.

2023
Medical Oncology Assoc. Prof.
Istanbul Medipol University Department of Medical Oncology, Istanbul, Turkey

INTERNATIONAL CLINICAL TRIALS:

1. Astefania - ROCHE

• Title: A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy
• Role: Subinvestigator

2. PFİZER

• Title: A Study Of Lorlatinib Versus Crizotinib In First-Line Treatment Of Patients With ALK-Positive NSCLC
• Role: Subinvestigator

3. RECITE - AMGEN

• Title: Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Gastrointestinal, Pancreatic, or Colorectal Cancer
• Role: Subinvestigator

4. NAVIGATE - BAYER

• Title: A Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors
• Role: Subinvestigator

5. RUBY - Tesaro (PRA)

• Title: A Phase 3, Randomized, Double-blind, Multicenter Study of Dostarlimab (TSR-042) Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel in Patients With Recurrent or Primary Advanced Endometrial Cancer
• Role: Subinvestigator

6. ENGOT-ov43/GOG-3036 - MSD

• Title: Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women With BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK001/ENGOT-ov43/GOG-3036)
• Role: Subinvestigator

7. ASTRA ZENECA

• Title: To Study Clinical Effectiveness and Safety of Olaparib Monotherapy in Metastatic Breast Cancer Patients.
• Role: Subinvestigator

8. ROSY-O - ASTRA ZENECA

• Title: Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib
• Role: Subinvestigator
•  

INTERNATIONAL PUBLICATIONS

I. Published journal articles indexed by SCI, SSCI, and AHCI

Weekly Paclitaxel in Classic Kaposi Sarcoma

• Authors: Paksoy, N., Khanmammadov, N., Doğan, İ., Ferhatoğlu, F., Ahmed, M. A., Karaman, S., & Aydiner, A.
• Journal: Medicine, 102(5)

Carboplatin Desensitization in Ovarian Carcinoma

• Authors: Paksoy, N., Khanmammadov, N., Doğan, İ., Ferhatoğlu, F., Yildiz, A., Ak, N., & Aydiner, A.
• Journal: Medicine, 101(45), e31726

High-Dose Chemotherapy for Ewing’s Sarcoma

• Authors: Paksoy, N., Ferhatoglu, F., Dogan, İ., Khanmammadov, N., Celik, A. I., Gulbas, Z., & Başaran, M.
• Journal: Medicine, 101(49), e32213

Multidrug Refractory TFE3(+) Renal Cell Carcinoma

• Authors: Paksoy, Nail, et al.
• Journal: Journal of Oncology Pharmacy Practice, 2022, 28.1: 215-221

Crizotinib Efficacy in NSCLC with MET Alterations

• Authors: Gürbüz, M., Kiliçkap, S., Bilici, A., Karadurmuş, N., Sezer, A., Şendur, M. A. N., ... & Demirkazik, A.
• Journal: Medicine, 101(50), e32368

Clinicopathological Features in ALK Mutant NSCLC

• Authors: Dogan, I., Gurbuz, M., Paksoy, N., Ferhatoglu, F., Vatansever, S., Saip, P., ... & Aydiner, A.
• Journal: Medicine, 101(34)

PSMA-Based Tumor Burden in Prostate Cancer

• Authors: HAS SIMSEK, Duygu, et al.
• Journal: Annals of Nuclear Medicine, 2021, 35.6: 680-690

Atezolizumab in Metastatic Urothelial Carcinoma

• Authors: TURAL, Deniz, et al.
• Journal: European Urology Focus, 2021, 7.5: 1061-1066

Pulmonary Sarcomatoid Carcinoma

• Authors: FERHATOGLU, Ferhat, et al.
• Journal: Oncology Research and Treatment, 2021, 44.11: 590-601

Prognostic Factors in Atezolizumab-Treated Urothelial Carcinoma

• Authors: TURAL, Deniz, et al.
• Journal: International Journal of Clinical Oncology, 2021, 26.8: 1506-1513

Atezolizumab with Chemotherapy in Small Cell Lung Cancer

• Authors: GÜRBÜZ, Mustafa, et al.
• Journal: Journal of Cancer Research and Clinical Oncology, 2022, 1-9

FOLFIRINOX vs. Gemcitabine + Nab-Paclitaxel in Pancreatic Cancer

• Authors: AY, Seval, et al.
• Journal: Journal of Chemotherapy, 2022, 1-7

Trastuzumab Emtansine in Older HER2-Positive Breast Cancer Patients

• Authors: CIL, Ibrahim, et al.
• Journal: Tumori Journal, 2022, 108.1: 19-25

Real-Life Efficacy of Osimertinib in Advanced NSCLC

• Authors: HIZAL, Mutlu, et al.
• Journal: Journal of Cancer Research and Clinical Oncology, 2022, 148.6: 1501-1508

ALK-Positive Cells Percentage and Alectinib Efficacy

• Authors: Hizal, M., Bilgin, B., Paksoy, N., Atcı, M. M., Kahraman, S., Kılıçkap, S., ... & Şendur, M. A. N.
• Journal: Journal of Cancer Research and Clinical Oncology, 149(8), 4141-4148

Real-World Data on Alectinib in ALK-Positive NSCLC

• Authors: Hizal, M., Bilgin, B., Paksoy, N., Kılıçkap, S., Atcı, M. M., Kahraman, S., ... & Şendur, M. A. N.
• Journal: Future Oncology, 18(23), 2573-2582

Prognostic Factors in Metastatic RCC with T790M Mutation

• Authors: Dogan, I., Iribas, A., Paksoy, N., Vatansever, S., & Basaran, M.
• Journal: Journal of Cancer Research and Therapeutics

FLOT Regimen in Metastatic Gastric Cancer

• Authors: Tastekin, D., Paksoy, N., Dogan, I., Ferhatoglu, F., Khanmammadov, N., Bozbey, H. U., & Karabulut, S.
• Journal: Journal of Cancer Research and Therapeutics

Desensitization Protocol in Lenalidomide Hypersensitivity Reactions

• Authors: DEMIR, Semra, et al.
• Journal: Annals of Allergy, Asthma & Immunology, 2019, 123.4: 394-397

Factors Associated with Diagnostic Skin Test Positivity in PPI Hypersensitivity

• Authors: ÖZDEMIR, Seçil Kepil, et al.
• Journal: Allergy, 2019, 74.6: 1187-1190

Efficacy of Capecitabine and Temozolomide in Neuroendocrine Tumors

• Authors: Ünal, Ç., Azizy, A., Karabulut, S., Taştekin, D., Akyıldız, A., Yaşar, S., ... & Sağlam, S.
• Journal: The Oncologist, oyad257

Subsequent Treatments in Hormone-Positive Breast Cancer Progression

• Authors: Karacin, C., Oksuzoglu, B., Demirci, A., Keskinkılıç, M., Baytemür, N. K., Yılmaz, F., ... & Hacıbekiroğlu, İ.
• Journal: BMC cancer, 23(1), 192

Termination of Trastuzumab in HER2-Positive Metastatic Breast Cancer

• Authors: Dogan, I., Aydin, E., Khanmammadov, N., Paksoy, N., Saip, P., & Aydiner, A.
• Journal: Scientific Reports, 13(1), 8779

Long-term Outcomes and Predictors of Recurrence in Node-Negative Early Stage Breast Cancer

• Authors: Dogan, I., Aydin, E., Khanmammadov, N., Paksoy, N., Ferhatoğlu, F., Ak, N., ... & Aydiner, A.
• Journal: Journal of Cancer Research and Clinical Oncology, 1-9

Prognostic Factors Influencing PFS in HER2-Positive Metastatic Breast Cancer

• Authors: Doğan, İ., Paksoy, N., Ak, N., Vatansever, S., Saip, P., & Aydıner, A.
• Journal: European Journal of Breast Health, 19(2), 128

Treatment Efficacy of Ribociclib or Palbociclib plus Letrozole in Metastatic Breast Cancer

• Authors: Kahraman, S., Erul, E., Seyyar, M., Gumusay, O., Bayram, E., Demirel, B. C., ... & Nahit Sendur, M. A.
• Journal: Future Oncology, 19(10), 727-736

Efficacy and Safety of Sorafenib in Adult Metastatic Osteosarcoma Patients

• Authors: Dogan, I., Paksoy, N., & Basaran, M.
• Journal: Journal of Cancer Research and Therapeutics

Single-Agent Temozolomide as Salvage Therapy in Heavily Pretreated Metastatic Sarcoma Patients

• Authors: Dogan, I., Paksoy, N., & Basaran, M.
• Journal: Journal of Cancer Research and Therapeutics

Outcomes and Prognostic Factors in Metastatic Renal Cell Carcinoma with Brain Metastases

• Authors: Dogan, I., Iribas, A., Paksoy, N., Vatansever, S., & Basaran, M.
• Journal: Journal of Cancer Research and Therapeutics

FLOT Regimen in First-Line Treatment of Metastatic Gastric Cancer

• Authors: Tastekin, D., Paksoy, N., Dogan, I., Ferhatoglu, F., Khanmammadov, N., Bozbey, H. U., & Karabulut, S.
• Journal: Journal of Cancer Research and Therapeutics

Prognostic Factors of Perioperative FLOT Regimen in Operable Gastric Cancer

• Authors: Erol, C., Sakin, A., Basoglu, T., Ozden, E., Cabuk, D., Dogan, M., ... & Sendur, M. A. N.
• Journal: [Not specified]

Efficacy and Outcomes of Systemic Chemotherapy in Posttransplant Kaposi Sarcoma

• Authors: Khanmammadov, N., Paksoy, N., Doğan, I., Ferhatoğlu, F., Saip, P., & Aydiner, A.
• Journal: Medicine, 102(39), e35383

Comparison of Second-Line Treatments in Metastatic Renal Cell Carcinoma

• Authors: Pehlivan, M., Paksoy, N., Aydin, E., Basaran, M., & Ekenel, M.
• Journal: Medicine, 102(41), e35245

Toxicity Management and Effectiveness of Regorafenib in Advance GIST Patients: A Real-world Study - Authors: Paksoy, N., Ferhatoğlu, F., Doğan, İ., Khanmammadov, N., Bozbey, H. U., Karabulut, S., & Taştekin, D. - Journal: TURKISH JOURNAL OF ONCOLOGY, 1(1)

Demographic and Clinical Features and Factors Associated with Survival in Patients with Primary Glomerulonephritis: Single Tertiary Center Experience - Authors: Paksoy, N., Trabulus, S., Seyahi, N., & Altiparmak, M. R. - Journal: Namik Kemal Tip Dergisi, 11(1)

Efficacy of Sorafenib in Symptomatic Patients with Pretreated Progressive Desmoid Tumors - Authors: Paksoy, N., Ferhatoglu, F., Dogan, I., Ak, N., Pehlivan, M., Ekenel, M., & Basaran, M.

Nodal Response to Neoadjuvant Chemotherapy is a Better Predictive Factor of Survival Than Miller-Payne Scoring in Breast Cancer - Authors: Ak, Naziye, et al. - Journal: Journal of Oncological Sciences, 7.2: 42-49

Evaluation of Prognostic and Predictive Values of Hemogram Parameters in Patients with Advanced Stage Ovarian Carcinoma - Authors: Ak, Naziye, et al. - Journal: Turkish Journal of Oncology/Türk Onkoloji Dergisi, 2021, 36.4

Identifying Risk Factors Associated with Survival and Drug-Related Toxicities in Imatinib-Resistant Gastrointestinal Stromal Tumor (GIST) Patients Treated with Sunitinib - Authors: Ferhatoglu, F., Karabulut, S., Paksoy, N., & Tastekin, D.

Real-life Outcomes of ROS1 Fusion-positive Metastatic Lung Cancer Patients who were Treated with Crizotinib - Authors: Dogan, İ., Khanmammadov, N., Paksoy, N., Ferhatoglu, F., Aydın, E., Vatansever, S., & Aydine, A. - Journal: TURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGY

Predictors of the acquisition of T790M mutation in EGFR-mutant metastatic lung cancer patients who were treated with EGFR inhibitors - Authors: Dogan, I., Khanmammadov, N., Paksoy, N., Vatansever, S., Saip, P., & Aydıner, A. - Journal: Eurasian Journal of Pulmonology

Laterality of Adrenal Gland Metastasis in Lung Cancer: Results of a Comparative Study - Authors: Ferhatoglu, F., Gagatay, T., Okumus, G., Aydiner, A., Paksoy, N., Ak, N., ... & Saip, P. - Journal: Eurasian Journal of Medical Investigation, 7(2)

Poor Risk Factors Affecting Cancer Patients Infected with Covid-19: A Retrospective Comparative Study from a Pandemic Hospital - Authors: Ferhatoglu, F., Kapağan, T., Paksoy, N., Ak, N., Medetalibeyoğlu, A., Şenkal, N., ... & Vatansever, S. - Journal: Turk Onkoloji Dergisi, 38(1)

Systemic Treatment Outcomes of Progressive Medullary Thyroid Carcinoma from the Registries of a Tertiary Cancer Center - Authors: Ferhatoglu, F., Paksoy, N., & Başaran, M. - Journal: Namik Kemal Tip Dergisi, 10(4)

Evaluation of clinical features and risk factors related to late recurrence (> 5 years) in patients with breast cancer - Authors: Ferhatoglu, F., Aydiner, A., & Paksoy, N. - Journal: Journal of Surgery & Medicine (JOSAM), 6(12)

Assessing the Clinical Impact of Lutetium-177 DOTATATE Peptide Receptor Radionuclide Therapy (PRRT) on Metastatic Neuroendocrine Tumors: A Multicenter Real-World Data from Türkiye

Thesis:

Istanbul University Cerrahpaşa Medical Faculty, Internal Medicine Department PAKSOY, Nail. Demographical, clinical characteristics and survival factors in patients withprimary glomerulonephritis: Cerrahpasa Medical Faculty Experience. (2016)

International Refereed Congress / Symposium Publications in Proceedings (ASCO/ESMO Abstracts)

Prognostic factors influencing progression-free survival in HER2 positive metastatic breast cancer patients who treated with lapatinib and capecitabine combination

• Authors: Dogan, I., Paksoy, N., Ak, N., Vatansever, S., Saip, P., & Aydiner, A. (2022)

Efficacy of regorafenib and 5-fluorouracil-based rechallenge treatment in the third-line treatment of metastatic colorectal cancer: A Turkish oncology group study

• Authors: Şenocak Taşçi, E., Oyan, B., Sonmez, O., Mutlu, A. U., Atcı, M. M., Oner, I., ... & Gulmez, A. (2022)

Long-term outcomes and predictors of recurrence in patients with early-stage node-negative breast cancer

• Authors: Dogan, I., Aydin, E., Paksoy, N., Ferhatoglu, F., Ak, N., Ibis, K., ... & Aydiner, A. (2021)

Efficacy of temozolomide in pretreated patients with metastatic sarcoma

• Authors: Paksoy, N., Dogan, I., Ekenel, M., & Basaran, M. (2021)

Efficacy of sorafenib in symptomatic patients with pretreated progressive desmoid tumors

• Authors: Ferhatoglu, F., Paksoy, N., Dogan, I., Ak, N., Pehlivan, M., Ekenel, M., & Basaran, M. (2021)

Efficacy of sorafenib in heavily pretreated adult patients with metastatic osteosarcoma

• Authors: Paksoy, N., Dogan, I., Ekenel, M., & Basaran, M. (2021)

Outcomes and prognostic factors in metastatic renal cell carcinoma patients with brain metastases

• Authors: Dogan, İ., Iribas, A., Paksoy, N., Ekenel, M., Vatansever, S., & Basaran, M. (2021)

Association of response to first-line chemotherapy with the efficacy of atezolizumab in patients with metastatic urothelial carcinoma

• Authors: Tural, D., Olmez, O. F., Sümbül, A. T., Artac, M., Ozhan, N., Akar, E., ... & Erman, M. (2021)

Safety and survival in adult women with platinum-sensitive relapsed BRCA mutant ovarian cancer: A study of patients in Olaparib Turkey Early Access Program—LynTurk study

• Authors: Esin, E., Ahmed, M. A., Yıldırım, H. Ç., Mandel, N. M., Erdemoglu, E., Sari, M., ... & Paydas, S. (2023)

Atezolizumab in patients with metastatic urothelial carcinoma who have progressed after first-line chemotherapy: Results of real-life experiences

• Authors: Tural, D., Ölmez, Ö. F., Sümbül, A. T., Artaç, M., Özhan, N., Akar, E., ... & Kılıçkap, S. (2021)

Experience

2019 - 2022 Medipol University

2010 Private Nisa Hospital

2008 - 2010 Kaman State Hospital

Education

2008

Istanbul University Cerrahpaşa Faculty of Medicine, Obstetrics and Gynecology

2002

Istanbul University, Istanbul Faculty of Medicine

Position:

Associate Professor ,

General Surgery Department

ISTANBUL MEDIPOL UNIVERSITY PENDIK HOSPITAL General Surgery Department

PERSONAL INFORMATION

Birth Date: 14.05.1982 

Place of Birth      : Şanlıurfa, Türkiye

Married, father of one.

CITIZENSHIP:

Republic of Turkey

EDUCATION:

Specialization:

General Surgery Department

Istanbul Kartal Dr. Lütfü Kırdar Training and Research Hospital (2009- 2014)

University

Istanbul University Istanbul Faculty of Medicine (20022008)

Anadolu University Faculty of Business Administration - Administration of Health Institutions (2013-2015)

Anadolu University Faculty of Open Education Department of Law (2016-)

High school

Erzincan Science High School (1998-2002)

Working Experience:

ERZINCAN NEVZAT AYAZ SCIENCE HIGH SCHOOL 1998-2002

ISTANBUL UNIVERSITY ISTANBUL FACULTY 2002-2009

GENERAL SURGERY ASSISTANT ISTANBUL KARTAL DR. LUTFI KIRDAR TRAINING AND RESEARCH HOSPITAL 2009-2014

SPECIALIST PHYSICIAN MEDENIYET UNIVERSITY GOZTEPE TRAINING AND RESEARCH HOSPITAL 2014-2015

CHIEF PHYSICIAN T.R.  MINISTRY OF HEALTH SILOPI STATE HOSPITAL 2015-2016

SPECIALIST PHYSICIAN T.R. MINISTRY OF HEALTH DERINCE TRAINING AND RESEARCH HOSPITAL, 2018-2020

SPECIALIST PHYSICIAN SANLIURFA MEHMET AKIF INAN TRAINING AND RESEARCH HOSPITAL 2016-2018

ASSOCIATE PROFESSOR ISTANBUL KARTAL DR. LUTFI KIRDAR CITY HOSPITAL 2020-2023

İSTANBUL MEDIPOL UNIVERSITY PENDIK HOSPITAL 2023-

PUBLICATIONS

National and International Articles

1 GÖK MEHMET ALİ, KAFADAR MEHMET TOLGA (2021). Inguinal hernia repair via laparoscopic transabdominal preperitoneal (TAPP) method: Our 2 years clinical results. Annals of Medical Research, 28(4), 812-815., Doi: 10.5455/annalsmedres.2020.05.443

2 SAĞIROĞLU ŞÜKRİYE JÜLİDE, ÖZDEMİR TUĞRUL, ATAK TUBA, GÖK MEHMET ALİ, ORHUN ERDOĞAN KIVILCIM, EREN TURGUT TUNÇ, ALİMOĞLU ORHAN (2016). Laparoscopic Total Extraperitoneal Inguinal Hernia Repair Without Mesh Fixation: Report of Early Outcomes. SouthernPrint Date :22/10/2022 17:41:41 Clinics of Istanbul Eurasia, 27(3), 215-219., Doi: 10.14744/scie.2017.64872 

3 ÇİFTÇİ ALİ, GÖK MEHMET ALİ, KAFADAR MEHMET TOLGA (2022). Management of Acute Biliary Pancreatitis in Cholecystectomized Patients. Bezmiâlem Science, 10(4), 507-511. Doi: 10.14235/ bas galenos. 2021.6708

4 GÖK MEHMET ALİ, YEĞEN SERKAN FATİH, KAFADAR MEHMET TOLGA, KOCAOĞLU AYTAÇ EMRE (2022). Gastrointestinal Stromal Tümörlerde İmmünohistokimyasal Markırların ve Tümör Boyutunun Prognoz Üzerindeki Rolü. Kocaeli Tıp Dergisi, 10(2), 101-104. M-784-1650 KAFADAR MEHMET TOLGA, GÖK MEHMET ALİ (2022). Laparoscopic transabdominal preperitoneal repair of strangulated femoral hernia: Superiority of an unusual emergency surgical approach due to a case. Annals of Medicine and Surgery, 36(1), 110-112.

5 GÖK MEHMET ALİ, KARADAYI BÜYÜKÖZSOY AYŞEGÜL, KAFADAR MEHMET TOLGA (2022). The sensitivity of ultrasound in the clinical diagnosis of inguinal hernias in adults: a comparative study. Journal of Ultrasound, 1-4., Doi: 10.1007/s40477-021-00641-4

6 KARADAYI BÜYÜKÖZSOY AYŞEGÜL, KARATAY EMRAH, GÖK MEHMET ALİ (2022). Comparison of the Effectiveness of Ultrasound Imaging and Perioperative Measurement in the Diagnosis and Characterization of Incisional Hernia. Journal of Medical Ultrasound, 1-5.

7 GÖK MEHMET ALİ, DEMİR MUSTAFA, YEĞEN SERKAN FATİH, KAFADAR MEHMET TOLGA, ŞENOL METİN, KOCAOĞLU AYTAÇ EMRE, AKIN EMRAH (2022). Endoscopic Intra-gastric Botulinum Toxin A for Obesity Treatment: IsIt Effective?. Kocaeli Tıp Dergisi, 11(2), 149-152.

8 GÖK MEHMET ALİ, KARATAY EMRAH, ÇİFTÇİ ALİ (2022). İnguinal Hernilerde Balonsuz ve Mesh Sabitleyicisiz Laparoskopik Total Ekstraperitoneal Onarımın Cerrahi Deneyim ile Korelasyonu. Dicle Medical Journal, 49(3), 498-503., Doi: 10.5798/dicletip.1170263

9 KAFADAR MEHMET TOLGA, GÖK MEHMET ALİ (2022). Effects of Carvedilol on Liver İschemiaReperfusion İnjury in Rats. Ulusal Travma ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery, 28(7), 885-893.

10 ŞENOL METİN, GÖK MEHMET ALİ (2022). Small Bowel Obstruction due to Phytobezoar. Kocaeli Tıp Dergisi, 11(2), 1-6.

11 KARATAY EMRAH, GÖK MEHMET ALİ, JAVADOV MIRKHALIG (2021). Measurement of hiatal surface area and other hiatus oesophageal diameters at computed tomography imaging in patients with gastroesophageal reflux disease and its relationship with hiatal hernia. Journal of Minimal Access Surgery, 17(4), 537-541., Doi: 10.4103/jmas.JMAS_175_20

12 GÖK MEHMET ALİ, KAFADAR MEHMET TOLGA, YEĞEN SERKAN FATİH (2021). Perforated colorectal cancers; clinical outcomes \nof 18 patients who underwent emergency surgery. Gastroenterology Review, 16(2), 161-165., Doi: 10.5114/pg.2021.106667

13 YEĞEN SERKAN FATİH, KAFADAR MEHMET TOLGA, GÖK MEHMET ALİ (2020). Comparison of Perioperative Standard and Immunomodulating Enteral Nutrition in Patients Received Major Abdominal Cancer Surgery: a Prospective, Randomized, Controlled Clinical Trial. Indian Journal of Surgery, 82, 828-834., Doi: 10.1007/s12262-020-02114-0 

14 GÖK MEHMET ALİ, KAFADAR MEHMET TOLGA, YEĞEN SERKAN FATİH (2020). Effects of Preoperative Oral Carbohydrate Loading on Preoperative and Postoperative Comfort in Patients Planned to Undergo Elective Cholecystectomy: A Prospective Randomized Controlled Clinical Trial. Iranian Red Crescent Medical Journal, 22(11), 1-6., Doi: 10.32592/ircmj.2020.22.11.107

15 GÖK MEHMET ALİ, KAFADAR MEHMET TOLGA, YEĞEN SERKAN FATİH (2019). Comparison of negative-pressure incision management system in wound dehiscence: A prospective, randomized, observational study. Journal of Medicine and Life, 12(3), 276-283., Doi: 10.25122/jml-2019-0033

16 KAFADAR MEHMET TOLGA, YALÇIN METİN, DADÜK YILDIRAY, SOYALP MURAT, GÖK MEHMET ALİ (2018). Laparoscopic Cholecystectomy for Acute Cholecystitis in Situs Inversus Totalis: An Extraordinary Approach. Eurasian Journal of Emergency Medicine, 17(2), 82-84.

17 KAFADAR MEHMET TOLGA, TEKER İBRAHİM, GÖK MEHMET ALİ, UĞURLU ESAT TAYLAN, ÇETİNKAYA ISMAİL (2018). Atraumatic splenic rupture secondary to abscess in a hemodialysis patient: a rare and fatal cause of acute abdomen diagnosed late. Journal of Surgical Case Reports,5, 1-3., Doi: 10.1093/jscr/rjy103

18 KAYA FERUDUN, KAFADAR MEHMET TOLGA, KISMET KEMAL, GÖK MEHMET ALİ, ERTAŞ ERTUĞRUL (2018). Congenital Transmesenteric Hernia Without Bowel Strangulation in a Young Adult. The Medical Bulletin Of Haseki, 56(4), 337-340., Doi: 10.4274/haseki.galenos.2022.8361

19 GÖK MEHMET ALİ, KAFADAR MEHMET TOLGA, GÜNEŞ ABDULLAH (2018). Laparoscopic treatment of hepatic hydatid disease: Şanlıurfa-Turkey experience and early clinical outcomes. Laparoscopic Endoscopic Surgical Science, 25(3), 98-102., Doi:14744/less.2018.4353171203046744-1078.03 Basım Tarihi 22/10/2022 17:41:41 Sayfa: 2

20 KAFADAR MEHMET TOLGA, YALÇIN METİN, GÖK MEHMET ALİ, AKTAŞ AYŞEGÜL, YÜREKLİ TACİTTİN SEMİH, ARSLAN AYŞEGÜL İSAL (2017). intraparenchymal Leiomyoma of the Breast: A Rare Location for an Infrequent Tumor. intraparenchymal Leiomyoma of the Breast: A Rare Location for an Infrequent Tumor, 13(3), 156-168., Doi: 10.5152/ejbh.2017.3472

 21 GÖK MEHMET ALİ, KAFADAR MEHMET TOLGA, ÖTER VOLKAN (2017). Early-term elective laparoscopic resection after endoscopic detorsion in cases with sigmoid colonic volvulus. Annals of Clinical and Analytical Medicine, 8(6), 492-495., Doi: 10.4328/JCAM.5231

22 KAFADAR MEHMET TOLGA, GÖK MEHMET ALİ, ÖTER VOLKAN (2017). Late-diagnosed penetrating stab Wounds in diaphragm and herniation. Annals of Clinical and Analytical Medicine, 8(4), 367-369., Doi: 10.4328/JCAM.5103

23 ANADOLULU ALİ İHSAN, KAFADAR MEHMET TOLGA, GÖK MEHMET ALİ, ANADOLULU ZEYNEP (2017). Laparoscopic spleen-preserving distal pancreatectomy with splenic vessel preservation for pancreatic pseudocyst in a 10-year-old boy. Journal of Pediatric Surgery Case Reports, 34(1), 10-12.

Proceedings

National and International Proceedings

İnguinal Hernilerde Total Ekstraperitoneal Onarımda Balon Disseksiyonu ile Teleskopik Disseksyonun   Kıyaslanması, KAFADAR MEHMET TOLGA, GÖK MEHMET ALİ (2022). 22.. Ulusal Cerrahi Kongresi, 

İNSİZYONEL HERNİLERDE LAPAROSKOPİK VE KONVANSİYONEL ONARIM YÖNTEMLERİ ARASINDAPOSTOPERATİF AĞRI, GÖK MEHMET ALİ, JAVADOV MIRKHALIG (2021). 8.. Ulusal Fıtık Kongresi

Laparaskopık total ekstraperıitoneal (TEP) onarımında redükte edilemeyen keseler enerji

cıihazıyla lıigate edılebırlıir mı , KAFADAR MEHMET TOLGA, GÖK MEHMET ALİ (2019). 7..

Ulusal Fıtık Kongresi

TEK İNSİZYON LAPARASKOPİK TOTAL EKSTRAPERİTONEAL İNGUİNAL HERNİ ONARIMI DENEYİMİMİZ, GÖK MEHMET ALİ, DEMİR MUSTAFA (2019). 14.. Endoskopik Laparoskopik Cerrahi Kongresi

Laparaskopik Sleeve Gastrektomide 3D Görüntüleme Sisteminin Etkiniliği , GÖK MEHMET ALİ, KAYA FERUDUN, KAFADAR MEHMET TOLGA, AKSOY BAŞAR (2017). 2.. Bariatrik ve Metabolik Cerrahi Kongresi

İnsizyonel hernide laparaskopik preperitoneal onarım, GÖK MEHMET ALİ, KAFADAR MEHMET TOLGA (2017).. 9.. Cerrahi Araştırma Kongresi

ERCP Yapılan Kist Hidatikli Hastalarda Kist Küçülür mü, YALÇIN METİN, GÖK MEHMET ALİ, KAFADAR MEHMET TOLGA (2017).. 13.. Türk Hepatopankreatobilier Cerrahi Kongresi

İnsizyonel Hernilerde TAPP Onarım Mümkün mü, GÖK MEHMET ALİ, AKSOY BAŞAR, KAFADAR MEHMET TOLGA, YALÇIN METİN (2017).. 6.. Ulusal Fıtık Kongresi, (Özet bildiri)

HİATAL HERNİLERDE LAPAROSKOPİK YAKLAŞIM, GÖK MEHMET ALİ, YALÇIN METİN, KAFADAR MEHMET TOLGA, YILMAZ TACETTİN SEMİH, AKTAŞ AYŞEGÜL (2017).. 13.. Endoskopik Laparoskopik Cerrahi Kongresi

KLİNİĞİMİZDE İNGUİNAL HERNİDE 3 TEKNİĞİN KARŞILAŞTIRLMASI, YALÇIN METİN, GÖK MEHMET ALİ, ÇEKİÇ TOLGA FARUK, KABALAK BİLAL, ÖTER VOLKAN, AKTAŞ AYŞEGÜL (2017). Ulusal Endoskopik Laparoskopik Cerrahi Kongresi

Kolon Divertikül  Perforasyonlarında Hartmann Prosedürü veya Primer Anastomoz? , GÖK MEHMET ALİ, KEŞKÜŞ BRAHIM H. HÜDAVERDI, BÖZKURT AHMET ÇAĞLAR, YALÇIN METİN, YILMAZ TACETTİN SEMİH (2017).. 11.. Ulusal Travma ve Acil Cerrahi Kongresi, (Özet bildiri)

GASTROİNTESTİNAL PREKANSEROZ LEZYONLARDA ENDOSKOPİK MUKOZAL REZEKSİYONUN ROLÜ, ORMAN SÜLEYMAN, GÖK MEHMET ALİ, EREN TURGUT TUNÇ, LEBLEBİCİ METİN, ALİMOĞLU ORHAN (2015). 12.. Ulusal Endoskopik Laparoskopik Cerrahi Kongresi

PİYES MAMAOGRAFİSİNDE KİTLE YOK! NE YAPILMALIM, ESER MEHMET, HATİPOĞLU HAYAT, GÜNDOĞAN ERSİN, GÖK MEHMET ALİ, ÇETİN KENAN, ACAR AYLİN, TAN SEDAT, BİLDİK NECDET (2014).. 19.. Ulusal Cerrahi Kongresi

LAPAROSKOPİK KOLESİSTEKTOMİ YAPILAN HASTALARDA TROKAR YERİ FITIĞI GELİŞİMİNDE ETKİLİ OLABİLECEK FAKTÖRLERİN ARAŞTIRILMASI, GÖK MEHMET ALİ, KÜNDEŞ MUHAMMED FİKRİ, KEMENT METİN, ATICI ALİ EMRE, KAPTANOĞLU LEVENT, İLHAN NOYAN, CAN UĞUR, BİLDİK NEJDET, VURAL SELAHATTİN (2014).. 19.. ULUSAL CERRAHİ KONGRESİ 

Books

Written sections in international books

1)Genel Cerrahide Nadir Görülen Acil ve Elektif Vakalar, Bölüm adı:(Akciğere Fistülize Karaciğer Kist Hidatik Vakasına Acil Laparoskopik Yaklaşım) (2020)., COŞKUN MURAT, GÖK MEHMET ALİ,

Akademisyen Yayınevi, Editör: Ender ANILIR Mehmet BAYRAK Mehmet Tolga KAFADAR Mert TANAL Ali Emre NAYCI Hüseyin KILAVUZ Özlem Öndeş BAYAR, Basım sayısı:1, Sayfa Sayısı 655, ISBN:978- 625-7275-23-1, Türkçe(Bilimsel Kitap)

2)Gastrointestinal Sistem Kanserlerinin Cerrahisi, Bölüm adı:(Karaciğerin Primer Solid MalignNeoplazileri) (2020)., GÖK MEHMET ALİ, Akademisyen Yayınevi, Editör: Hüseyin Özgür AYTAÇ, Basım sayısı:1, Sayfa Sayısı 404, ISBN:978-605-258-949-6, Türkçe (Bilimsel Kitap)

3)Gastrointestinal Sistem Tümörleri-1, Bölüm adı:(ERKEN EVRE HASTALIKTA CERRAHİ TEDAVİ) (2019)., GÖK MEHMET ALİ, Akademisyen Yayınevi, Basım sayısı:1, Sayfa Sayısı 493, ISBN:978-605-258-551-1, Türkçe (Bilimsel Kitap)

Editorship

1) Minimal İnvaziv Cerrahi, Kitap, Editör, Akademisyen Kitapevi A.Ş., 22.10.2020-15.07.2021

2. YENİ NESİLCERRAHİ, Kitap, Editör, Akademisyen Kitapevi A.Ş., 15.06.2021-15.08.2022

3. Onkolojik Cerrahi, Kitap, Editör, Akademisyen Kitapevi A.Ş., 05.04.2021-05.12.2021

4.. Fıtık Cerrahisi, Kitap, Editör, Akademisyen Kitapevi A.Ş., 07.04.2020-07.11.2020

Certificates

Hernia A to Z Fundemantals Hands on Workshop, Laparoscopic Hernia Surgery Experience Certificate in Cadaver was awarded by the European Hernia Society.

. DUBAİ/ U.A.E, 28.11.2018 

CADAVER TRAINING EVENT IN COLON AND RECTAL SURGERY, Robotic Colorectal Surgery in Cadaver training certificate was given.  STONY BROOK UNİVERSİTY / NEWYORK/ USA,.04.2016

Memberships in Scientific Organizations:

1.. Turkish Society of Colon and Rectum Surgery, Member, 2020

2.. Turkish Surgical Association, Member, 2014

أخصائي أورام متخصص في علاج سرطان الجهاز الهضمي

رئيس قسم جراحة الثدي أخصائي أمراض الثدي

دكتور اورام

دكتور اورام

دكتور اورام. اخصائي علاج سرطان الثدي

أخصائي أشعة. استمع إلى معهد الأشعة التشخيصية والتداخلية

دكتور اورام

دكتور اورام

تخرج من مدرسة أنقرة للعلوم الثانوية واستكمل تدريبه في الطب الباطني في مستشفى إيلينغ العام بلندن ، بالإضافة إلى خدمته الإجبارية كممارس عام في سيرت 1984-1986. ثم أكمل إقامته في مستشفى Haydarpaşa Numune ، قسم التشخيص الإشعاعي ، وتخرج من جامعة الأناضول ، قسم إدارة الأعمال. حصل على ألقاب أستاذ مشارك وأستاذ في مجال الأشعة التشخيصية ونشر 47 مقالة ، 14 منها في الخارج و 33 منها محلية. يعمل حاليًا كعميد لكلية الطب بجامعة مالتيب ورئيس قسم الأشعة وعضو في جمعية الأشعة التركية وجمعية التصوير الطبي والأشعة التداخلية.