إيطاليا,
The clinic performs over 1,400 cardiac ablations annually — among the world's highest volumes for this procedure. Professor Carlo Pappone, who developed the internationally recognized 'Pappone approach', performs the circumferential pulmonary vein isolation using 3D CART mapping at San Donato Hospital. This IRCCS-certified research hospital meets standards set by the Italian Ministry of Health. The package, priced at about $20,080, covers physician fees, preoperative exams, the surgical procedure, and a 2–3 day hospital stay with single-room accommodation for a companion.