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complications or thrombosis risk."},"follow_up_visits":[{"purpose":"wound_check","requirement":"routine","after":{"min":14,"max":28,"unit":"days","qualifier":"Post-discharge surgical review"}},{"purpose":"assessment","requirement":"routine","after":{"min":30,"max":60,"unit":"days","qualifier":"Oncology review and adjuvant planning"}},{"purpose":"result_review","requirement":"routine","after":{"min":90,"max":120,"unit":"days","qualifier":"Typical first surveillance imaging and tumour markers, then periodic"}}],"indications":["Peritoneal metastases from appendiceal cancer or pseudomyxoma peritonei","Peritoneal mesothelioma","Selected colorectal peritoneal metastases","Selected ovarian cancer with peritoneal disease","Selected gastric cancer peritoneal disease"],"main_risks":["Anastomotic leak or bowel fistula","Intra-abdominal infection or abscess","Bleeding","Postoperative ileus or bowel obstruction","Pancreatitis","Venous thromboembolism","Pulmonary complications and pleural effusion","Renal toxicity and electrolyte disturbances","Myelosuppression","Prolonged hospitalization or need for reoperation","Perioperative mortality"],"pain":"Moderate to severe pain after major abdominal surgery in the first days, managed with multimodal analgesia (often epidural or regional blocks plus medication), then gradually improving.","preparation":["Multidisciplinary tumour board review","Staging CT/MRI and tumour markers; sometimes diagnostic laparoscopy","Cardiopulmonary, renal and hepatic fitness assessment and blood tests","Nutritional assessment and optimisation","Anaesthetic and ICU planning","Fasting and bowel preparation as instructed","Stoma counselling where relevant","Smoking cessation and informed consent"],"recovery_timeline":[{"phase":"Days 0-3","description":"ICU or high-dependency monitoring, pain control, fluid and electrolyte management.","restrictions":["Bed rest with assisted mobilisation","Nothing by mouth initially"]},{"phase":"Days 4-21","description":"Gradual return of bowel function and diet, drain removal, mobilisation, discharge when stable.","restrictions":["No lifting","Dietary progression"]},{"phase":"Weeks 3-8","description":"Home recovery, fatigue improving, wound healing, nutrition rebuilding; possible adjuvant chemotherapy planning.","restrictions":["Avoid heavy lifting and strenuous activity"]},{"phase":"Months 2-4","description":"Return to ordinary activities and work for many patients; start of surveillance.","restrictions":["Gradual increase in activity as tolerated"]}],"rehabilitation_days":{"min":42,"max":90,"unit":"days","qualifier":"Ordinary functional recovery after cytoreductive surgery with HIPEC; fatigue may persist longer."},"result_longevity":"Benefit is disease control, not cure for all. Durability varies by tumour type and completeness of cytoreduction; some patients remain disease-free for years, others recur and need surveillance.","revision_rate_pct":{"min":5,"max":15,"unit":"percent","qualifier":"Unplanned return to theatre within 30-90 days, e.g. for leak, bleeding or abscess"},"scars":"Long midline abdominal incision (xiphoid to pubis) is typical, plus drain sites; a stoma may be needed in some patients.","sessions_or_stages":{"sessions":{"min":1,"max":1,"unit":"visits","qualifier":"One combined operation: cytoreductive surgery followed by HIPEC perfusion."},"stages":[{"code":"cytoreduction","label":"Cytoreductive surgery removing visible tumour and affected tissue","after":{"min":0,"max":0,"unit":"days","qualifier":"Same operation"}},{"code":"hipec_perfusion","label":"Heated intraperitoneal chemotherapy perfusion (typically 30-90 minutes)","after":{"min":0,"max":0,"unit":"days","qualifier":"Same operation, after cytoreduction"}},{"code":"reconstruction","label":"Bowel reconstruction or closure","after":{"min":0,"max":0,"unit":"days","qualifier":"Same operation"}}],"qualifier":"Single operative session with sequential stages."},"success":{"metric":"5-year overall survival after complete cytoreduction with HIPEC","value":50,"unit":"percent","horizon":"5 years","population":"Adults with peritoneal metastases, mixed tumour types, complete or near-complete cytoreduction","evidence_status":"limited"},"techniques":[{"name":"Open (coliseum) HIPEC with cytoreductive surgery","suits_whom":"Patients with peritoneal surface malignancy where abdomen is kept open during perfusion for uniform heat distribution and surgeon access.","recovery":"Inpatient stay of about 10-21 nights; recovery over several weeks to months."},{"name":"Closed-abdomen HIPEC with cytoreductive surgery","suits_whom":"Patients with peritoneal surface malignancy where the abdomen is closed before perfusion to maintain temperature and reduce exposure.","recovery":"Similar to open technique: about 10-21 nights inpatient and recovery over weeks to months."}],"treatment_conditions":["inpatient"],"treatment_duration_hours":{"min":6,"max":12,"unit":"hours","qualifier":"Complete operation, cytoreductive surgery plus HIPEC perfusion; varies with disease extent."},"initial_assessment_documents":["Histopathology report of primary tumour or biopsy","Contrast CT of chest, abdomen and pelvis","Abdominopelvic MRI report","Tumour marker blood results","Previous operative and chemotherapy reports","Recent kidney and liver function blood tests"],"travel_trips":{"min":1,"max":1,"one_trip_possible":true,"qualifier":"Single combined operation; about 10-21 nights inpatient until discharge and fitness to fly. Surveillance usually at home."},"clinic_checks":{"status":"ok","items":[{"id":"C1","text":"Check the surgeon's established track record with these complex operations. Why: the operation is complex, so experience matters","scope":"procedure","source":{"url":"https://stonybrookmedicine.edu/node/2289","host":"stonybrookmedicine.edu","quote":"Patients should seek surgeons with established track records of performing these complex operations.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"C2","text":"Check the qualifications of the medical team that will treat you","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"Have you checked the qualifications of the medical team treating you?","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"C3","text":"Get a second opinion from a doctor at home on whether the treatment is necessary and what options exist","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"A doctor can give you a valuable second opinion as well as advice about treatment options and whether it's necessary.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"C4","text":"Find out whether follow-up care is scheduled at the same facility as the procedure","scope":"treatment_abroad","source":{"url":"https://www.cdc.gov/yellow-book/hcp/health-care-abroad/medical-tourism.html","host":"cdc.gov","quote":"Medical tourists should also know whether follow-up care is scheduled to occur at the same facility as the procedure.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":403}},{"id":"C5","text":"Confirm the surgeon is trained and experienced in the exact procedure you are considering, not just in surgery generally","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Verify that the surgeon is trained and experienced in performing the procedure you are considering.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"red_flags":{"status":"ok","items":[{"id":"F1","text":"Pressure to make a quick decision about booking treatment abroad","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"pressure to make a quick decision","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"F2","text":"Booking advice from sales staff or travel agents is a red flag","scope":"treatment_abroad","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Do not accept advice from a travel agent, sales representatives or administrators.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"F3","text":"Being unable to speak directly with the treating clinician before booking is a red flag","scope":"treatment_abroad","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Speak directly to the doctor, dentist or nurse who will be carrying out your treatment before you book your trip.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"F4","text":"Being denied the chance to change your mind during the consultation is a red flag","scope":"treatment_abroad","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"You should be given the opportunity to change your mind during this consultation.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"warning_signs":{"status":"ok","items":[{"id":"W1","text":"Severe swelling, warmth or drainage at the incision","urgency":"contact_clinic","general":false,"source":{"url":"https://my.clevelandclinic.org/health/treatments/21569-hyperthermic-intraperitoneal-chemotherapy-hipec","host":"my.clevelandclinic.org","quote":"Severe swelling, warmth or drainage around your incision site","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"W2","text":"Nausea and vomiting that do not improve","urgency":"contact_clinic","general":false,"source":{"url":"https://my.clevelandclinic.org/health/treatments/21569-hyperthermic-intraperitoneal-chemotherapy-hipec","host":"my.clevelandclinic.org","quote":"Nausea and vomiting that don’t improve","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"W3","text":"Fever above 101 degrees F (38.3 degrees C)","urgency":"contact_clinic","general":true,"source":{"url":"https://my.clevelandclinic.org/health/treatments/21569-hyperthermic-intraperitoneal-chemotherapy-hipec","host":"my.clevelandclinic.org","quote":"Fever above 101 degrees F (38.3 degrees C)","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"take_home":{"status":"ok","items":[{"id":"T1","text":"Gives the home doctor treatment details and future care needs","document":"discharge letter for gp","source":{"url":"https://www.nhs.uk/nhs-services/hospitals/going-into-hospital/being-discharged-from-hospital","host":"nhs.uk","quote":"You'll also be given a letter for your GP, providing information about your treatment and future care needs.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"T2","text":"Ask for written details of the procedure before you leave the hospital","document":"written procedure details","source":{"url":"https://rcseng.ac.uk/patient-care/cosmetic-surgery/after-surgery/","host":"rcseng.ac.uk","quote":"After your surgery, before you leave the hospital, ask for written information about the procedure you've had.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T3","text":"Ask for copies of all prescriptions before you leave","document":"prescription copies","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Remember to ask for copies of all your treatment records, including prescriptions, scans and x-rays before you leave.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T4","text":"Home doctor needs the dates for required blood tests and follow-up appointments","document":"written aftercare plan","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"This should include any medication and doses, as well as any dates that blood tests and follow-up appointments must be carried out.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"alternatives":{"status":"ok","items":[{"id":"A1","text":"You would rather have several rounds of chemotherapy","name":"Systemic chemotherapy","source":{"url":"https://my.clevelandclinic.org/health/treatments/21569-hyperthermic-intraperitoneal-chemotherapy-hipec","host":"my.clevelandclinic.org","quote":"With systemic chemotherapy, treatment usually involves several sessions, or “rounds,” of chemotherapy.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200},"operation_id":null},{"id":"A2","text":"You want the standard surgery and IV chemotherapy option","name":"Surgery and IV chemotherapy","source":{"url":"https://www.healthline.com/health/cancer/hyperthermic-intraperitoneal-chemotherapy","host":"healthline.com","quote":"multiple studies have found that HIPEC has no greater benefit than the current standard of care (surgery and IV chemotherapy).","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200},"operation_id":null}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"technique_details":{"status":"ok","items":[{"id":"open-hipec","name":"Open (coliseum) HIPEC with 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surgeon.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1}}},"hrefLanguages":[{"rel":"alternate","hreflang":"ru","language":"ru","href":"https://ru.bookimed.com/clinics/country=israel/city=gercliya/procedure=gipertermicheskaya-vnutribrushinnaya-himioterapiya-hipec/"}],"questionsAndAnswers":[],"seoTests":{"thin_content":false,"no_txt_after_3_clinics":false},"offerFilters":{"offer_count":0,"city_filter":[{"id":5,"name":"رامات جان","alias":"ramat-gan","country_iso_code":"IL"}],"price_filter":{"from":0,"to":0,"avg":0}},"leadsCount":{"leads_count":1},"manualSeo":[],"updatedAt":"2026-11-13T20:40:16.895Z","activeCountries":["IL","TR","ES","TH"],"hasVideoReviewsByContext":true,"hasCriticalApiFallback":false}