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Durability varies with disease activity and baseline disability.","revision_rate_pct":null,"scars":"No surgical scars; only small marks at the venous catheter and injection sites.","sessions_or_stages":{"sessions":{"min":1,"max":1,"unit":"visits","qualifier":"One transplant course; usually completed within a single stay."},"stages":[{"code":"mobilization","label":"Stem cell mobilization with growth factor","after":{"min":0,"max":0,"unit":"days","qualifier":"Starts at the beginning of the protocol."}},{"code":"collection","label":"Stem cell collection by apheresis","after":{"min":5,"max":14,"unit":"days","qualifier":"Follows mobilization injections."}},{"code":"conditioning","label":"Immunosuppressive conditioning chemotherapy","after":{"min":14,"max":28,"unit":"days","qualifier":"Begins after collection and cell processing."}},{"code":"infusion","label":"Stem cell reinfusion","after":{"min":20,"max":35,"unit":"days","qualifier":"One to several days after conditioning ends."}},{"code":"engraftment","label":"Engraftment and blood count recovery","after":{"min":32,"max":49,"unit":"days","qualifier":"About 10-14 days after infusion, before discharge and travel home."}}],"qualifier":"Single autologous transplant course in sequential stages."},"success":{"metric":"No evidence of disease activity (NEDA)","value":70,"unit":"percent of patients","horizon":"5 years after transplant","population":"Adults with highly active relapsing-remitting MS treated with AHSCT","evidence_status":"limited"},"techniques":[{"name":"Autologous hematopoietic stem cell transplantation (AHSCT)","suits_whom":"Selected patients with highly active relapsing MS despite disease-modifying therapy.","recovery":"Inpatient stay of about 3-4 weeks, then several months of gradual recovery."},{"name":"Cyclophosphamide-based intermediate-intensity conditioning","suits_whom":"Patients suitable for lower-intensity regimens under protocol.","recovery":"Slightly shorter neutropenia; recovery over 2-4 months."},{"name":"BEAM-based conditioning","suits_whom":"Patients treated under protocols using higher-intensity regimens.","recovery":"Longer neutropenia and recovery of several months."}],"treatment_conditions":["inpatient","outpatient"],"treatment_duration_hours":{"min":1,"max":4,"unit":"hours","qualifier":"Stem cell reinfusion day only; the full protocol spans several weeks."},"initial_assessment_documents":["Brain and spinal cord MRI reports","Recent neurologist report with EDSS score","Relapse history with dates","List of previous MS disease-modifying therapies","Cerebrospinal fluid or oligoclonal band results (if available)","Recent blood tests including infection screening"],"travel_trips":{"min":1,"max":2,"one_trip_possible":true,"qualifier":"Autologous transplant (mobilization, collection, conditioning, infusion) usually takes one 5-8 week stay; some clinics split it into two trips."},"clinic_checks":null,"red_flags":null,"warning_signs":null,"take_home":null,"alternatives":null,"technique_details":null}},"hrefLanguages":[{"rel":"alternate","hreflang":"ru","language":"ru","href":"https://ru.bookimed.com/clinics/country=kolumbiya/city=medelin/procedure=lechenie-rasseyannogo-skleroza-stvolovymi-kletkami/"}],"questionsAndAnswers":[],"seoTests":{"thin_content":false,"no_txt_after_3_clinics":false},"offerFilters":{"offer_count":0,"price_filter":{"from":0,"to":0,"avg":0}},"leadsCount":{"leads_count":53924},"manualSeo":[],"updatedAt":"2026-11-12T04:00:15.828Z","activeCountries":["CO","TR","ES","TH"],"hasVideoReviewsByContext":true,"hasCriticalApiFallback":false}