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Exercise resumes gradually.","restrictions":["Daily skin, nail and mouth care","Maintain hydration","Increase exercise gradually, guided by oncology team"]},{"phase":"Weeks 6 to 12","description":"First response imaging and clinic review; initial response is judged and monitoring continues.","restrictions":["Continue treatment unless the oncology team advises otherwise"]},{"phase":"Ongoing therapy (months 3 to 6 and beyond)","description":"Daily therapy with periodic reviews and imaging until progression or intolerance; repeat testing if disease progresses.","restrictions":["Continue regular monitoring as scheduled","Do not stop or change dose without oncology advice"]},{"phase":"At any time","description":"Seek urgent care for new cough, breathlessness, fever, chest pain, palpitations, severe diarrhea, severe rash, eye pain, or infection or bleeding signs.","restrictions":["Do not wait for the next review","Team may pause the drug during assessment"]}],"rehabilitation_days":{"min":0,"max":7,"unit":"days","qualifier":"Oral therapy without procedure; time to settle into daily routine, affected by rash, diarrhea, fatigue and disease burden."},"result_longevity":"Disease control typically lasts months to a few years until resistance develops; median first-line progression-free survival was roughly 1.5 years. Benefit lasts only during therapy; not a cure.","revision_rate_pct":null,"scars":"None; no incisions.","sessions_or_stages":{"sessions":{"min":4,"max":8,"unit":"visits","qualifier":"Planned oncology reviews in the first 6 months from treatment start."},"stages":[{"code":"baseline_start","label":"Baseline assessment, counseling and start of daily oral therapy","after":{"min":0,"max":0,"unit":"days","qualifier":"Counted from treatment start."}},{"code":"early_tolerability_review","label":"Tolerability and laboratory review","after":{"min":14,"max":28,"unit":"days","qualifier":"After the first dose."}},{"code":"first_response_assessment","label":"First response imaging and clinic review","after":{"min":42,"max":84,"unit":"days","qualifier":"After the first dose; timing varies by clinic."}},{"code":"ongoing_scheduled_reviews","label":"Ongoing reviews with periodic imaging every 2 to 3 months","after":{"min":84,"max":180,"unit":"days","qualifier":"After the first dose; later intervals individualized."}}],"qualifier":"Daily oral osimertinib after biomarker confirmation, continued until progression or intolerance. 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time","scope":"treatment_type","source":{"url":"https://www.cancer.gov/about-cancer/treatment/types/targeted-therapies","host":"cancer.gov","quote":"But most of the time, your tumor will need to be tested to see if it contains targets for which there is a drug.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"red_flags":{"status":"ok","items":[{"id":"F1","text":"Promise that the doctor can know for certain how you will feel during treatment","scope":"treatment_type","source":{"url":"https://www.cancer.gov/about-cancer/treatment/types/targeted-therapies","host":"cancer.gov","quote":"Doctors and nurses cannot know for certain how you will feel during treatment.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},{"id":"F2","text":"Ad or quote calling targeted therapy free of serious side 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